Figure 5.

CAS regulates MMP-2 secretion and invasion of cancer cells. (a) CAS regulates MMP-2 secretion of MCF-7 cells. (b) Matrigel-based invasion assays of MCF-EV, MCF-CAS, and MCF-anti-CAS cells. Data represent the means of three independent experiments. (c) Immunoblotting of CAS expression in B16-EV, B16-CAS, and B16-anti-CAS cells. (d) CAS regulates MMP-2 secretion of B16-F10 cells. (e) Matrigel-based invasion assays of B16-CAS, B16-EV, and B16-anti-CAS cells. The upper is a representative photograph of the invaded cells. Data represent the means of three independent experiments.