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Positron Emission Tomography (PET) radiotracers in oncology – utility of 18F-Fluoro-deoxy-glucose (FDG)-PET in the management of patients with non-small-cell lung cancer (NSCLC)

Evelina Miele1,4 email, Gian Paolo Spinelli1,2,4 email, Federica Tomao1,4 email, Angelo Zullo3,4 email, Filippo De Marinis3,4 email, Giulia Pasciuti2,4 email, Luigi Rossi2,4 email, Federica Zoratto2,4 email and Silverio Tomao1,2,4 email

Department of Experimental Medicine University of Rome "Sapienza" viale Regina Elena 324, Rome, Italy

Operative Unit of Medical Oncology, S. Maria Goretti Hospital, University of Rome "Sapienza" – Latina-via Canova, Latina, Italy

Gastroenterology and Digestive Endoscopy, "Nuovo Regina Margherita" Hospital, Rome 00153, Italy

Thoracic Oncology Unit I, Department of Lung Diseases, San Camillo and Forlanini Hospitals, Rome, Italy

author email corresponding author email

Journal of Experimental & Clinical Cancer Research 2008, 27:52doi:10.1186/1756-9966-27-52

Published: 17 October 2008

Abstract

PET (Positron Emission Tomography) is a nuclear medicine imaging method, frequently used in oncology during the last years. It is a non-invasive technique that provides quantitative in vivo assessment of physiological and biological phenomena. PET has found its application in common practice for the management of various cancers.

Lung cancer is the most common cause of death for cancer in western countries.

This review focuses on radiotracers used for PET scan with particular attention to Non Small Cell Lung Cancer diagnosis, staging, response to treatment and follow-up


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