Microphotos of SKOV3 subcutaneous implanted tumor under TEM observation. (TEM × 10000). 6A: In response to SPEF exposure (1 kHz), the integrality of cell membrane was destroyed along with pyknosis, karyorrhexis and karyolysis. 6B: Typical characteristic of apoptosis was further induced by SPEF exposure (5 kHz).
Yang et al. Journal of Experimental & Clinical Cancer Research 2009 28:53 doi:10.1186/1756-9966-28-53