Table 2 |
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|
Somatostatin receptor subtypes mRNA in neuroendocrine tumours. |
|||||
| Tumor |
SSTR1 |
SSTR2 |
SSTR3 |
SSTR4 |
SSTR5 |
|
|
|||||
| Gastrinoma |
79%a |
93% |
36% |
61% |
93% |
| Insulinoma |
76% |
81% |
38% |
58% |
57% |
| N-F |
58% |
88% |
42% |
48% |
50% |
| Carcinoid (gut) |
76% |
80% |
43% |
68% |
77% |
|
SST, somatostatin receptor; N-F, Non functioning;a Indicates the percentage of positive tumours for each sst. mRNA expression may overestimate the number of receptors present, depending on the technique used [PR-polymerase chain reaction, Northern blot, in-situ hybridization]. [Data from Plöckinger U. Biotherapy. Best Practice & Research Clinical Endocrinology & Metabolism 2007; Vol. 21, No. 1, pp. 145-162] | |||||
Appetecchia and Baldelli Journal of Experimental & Clinical Cancer Research 2010 29:19 doi:10.1186/1756-9966-29-19 |
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