Biological characteristics of the CML MSCs. (A) The morphology of hemangioblasts from CML (Magnification × 200). (B) BCR/ABL fusion gene was detected by FISH (yellow signal is the positive one) in CML hemangioblasts from male patients. (C) BCR/ABL fusion gene was detected by RT-PCR(line4,6,8,10 correspond to non-special amplification).(D) Isotype analysis showed they were all persistently negative for CD34 and CD31 but positive for Flk1, CD29, CD44 and CD105.
Xishan et al. Journal of Experimental & Clinical Cancer Research 2011 30:47 doi:10.1186/1756-9966-30-47