Figure 2.

The effects of Flk-1+CD31-CD34- MSCs on T lymphocyte proliferation. (A) The effects of Flk-1+CD31-CD34- MSCs on T lymphocyte proliferation in mitogen proliferative assays. There are three groups, including nonstimulated T cells (none), PHA-stimulated T cells (Ts) and PHA-stimulated T cells cocultured with MSC at different ratios (MSC to T cell = 1:2, 1:10, :100). Data are shown as means ± S.D. of three independent experiments (*p < 0.05,**p < 0.005 vs. Ts). (B) The effects of Flk-1+CD31-CD34- MSCs on T lymphocyte proliferation in MLR. Flk-1+CD31-CD34- MSCs at 1:10 ratios (irradiated MSCs to T cells); there are four groups, including nonstimulated responder T cells (T0), irradiated stimulator cells plus responder T cells; normalMSC plusMLR (BMSC Ts), CML-derived MSC plus MLR (CML Ts). Data are shown as means ± S.D. of three independent experiments (*p ≥ 0.05,**p = 0.001 vs. Ts)

Xishan et al. Journal of Experimental & Clinical Cancer Research 2011 30:47   doi:10.1186/1756-9966-30-47
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