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1:

Combined effects of 5-fluorouracil, folinic acid and oxaliplatin on the expression of carcinoembryonic antigen in human colon cancer cells: pharmacological basis to develop an active antitumor immunochemotherapy.

Prete SP, Turriziani M, Massara MC, De Rossi A, Correale P, De Vecchis L, Torino F, Bonmassar L, Aquino A.

J Exp Clin Cancer Res. 2008 May 19;27:5.

PMID: 18577244 [PubMed - indexed for MEDLINE]

2:

Effect of the combined treatment with 5-fluorouracil, gamma-interferon or folinic acid on carcinoembryonic antigen expression in colon cancer cells.

Aquino A, Prete SP, Greiner JW, Giuliani A, Graziani G, Turriziani M, De Filippi R, Masci G, Bonmassar E, De Vecchis L.

Clin Cancer Res. 1998 Oct;4(10):2473-81.

PMID: 9796980 [PubMed - indexed for MEDLINE]

3:

Dendritic cell-mediated cross-presentation of antigens derived from colon carcinoma cells exposed to a highly cytotoxic multidrug regimen with gemcitabine, oxaliplatin, 5-fluorouracil, and leucovorin, elicits a powerful human antigen-specific CTL response with antitumor activity in vitro.

Correale P, Cusi MG, Del Vecchio MT, Aquino A, Prete SP, Tsang KY, Micheli L, Nencini C, La Placa M, Montagnani F, Terrosi C, Caraglia M, Formica V, Giorgi G, Bonmassar E, Francini G.

J Immunol. 2005 Jul 15;175(2):820-8. Erratum in: J Immunol. 2005 Nov 1;175(9):6235. Prete, Salvatore [corrected to Prete, Salvatore Pasquale].

PMID: 16002679 [PubMed - indexed for MEDLINE]

4:

Chemo-immunotherapy of metastatic colorectal carcinoma with gemcitabine plus FOLFOX 4 followed by subcutaneous granulocyte macrophage colony-stimulating factor and interleukin-2 induces strong immunologic and antitumor activity in metastatic colon cancer patients.

Correale P, Cusi MG, Tsang KY, Del Vecchio MT, Marsili S, Placa ML, Intrivici C, Aquino A, Micheli L, Nencini C, Ferrari F, Giorgi G, Bonmassar E, Francini G.

J Clin Oncol. 2005 Dec 10;23(35):8950-8. Epub 2005 Aug 1.

PMID: 16061910 [PubMed - indexed for MEDLINE]

5:

Increased expression of CEA and MHC class I in colorectal cancer cell lines exposed to chemotherapy drugs.

Ohtsukasa S, Okabe S, Yamashita H, Iwai T, Sugihara K.

J Cancer Res Clin Oncol. 2003 Dec;129(12):719-26. Epub 2003 Oct 15.

PMID: 14564514 [PubMed - indexed for MEDLINE]

6:

Drug-induced changes of carcinoembryonic antigen expression in human cancer cells: effect of 5-fluorouracil.

Prete SP, Aquino A, Masci G, Orlando L, Giuliani A, De Santis S, De Vecchis L, De Filippi R, Greiner JW, Bonmassar E, Graziani G.

J Pharmacol Exp Ther. 1996 Dec;279(3):1574-81.

PMID: 8968385 [PubMed - indexed for MEDLINE]

7:

Treatment of colon and breast carcinoma cells with 5-fluorouracil enhances expression of carcinoembryonic antigen and susceptibility to HLA-A(*)02.01 restricted, CEA-peptide-specific cytotoxic T cells in vitro.

Correale P, Aquino A, Giuliani A, Pellegrini M, Micheli L, Cusi MG, Nencini C, Petrioli R, Prete SP, De Vecchis L, Turriziani M, Giorgi G, Bonmassar E, Francini G.

Int J Cancer. 2003 Apr 20;104(4):437-45. Erratum in: Int J Cancer. 2003 Jul 20;105(6):882.

PMID: 12584740 [PubMed - indexed for MEDLINE]

8:

A novel method for monitoring response to chemotherapy based on the detection of circulating cancer cells: a case report.

Aquino A, Prete SP, Balduzzi A, Fossile E, Formica V, Torino F, Bonmassar L, Di Giacomo A, Cappelletti D, Cardillo A, Graziani G.

J Chemother. 2002 Aug;14(4):412-6.

PMID: 12420861 [PubMed - indexed for MEDLINE]

9:

Irinotecan or oxaliplatin combined with leucovorin and 5-fluorouracil as first-line treatment in advanced colorectal cancer: a multicenter, randomized, phase II study.

Kalofonos HP, Aravantinos G, Kosmidis P, Papakostas P, Economopoulos T, Dimopoulos M, Skarlos D, Bamias A, Pectasides D, Chalkidou S, Karina M, Koutras A, Samantas E, Bacoyiannis C, Samelis GF, Basdanis G, Kalfarentzos F, Fountzilas G.

Ann Oncol. 2005 Jun;16(6):869-77. Epub 2005 Apr 26.

PMID: 15855226 [PubMed - indexed for MEDLINE]

10:

Oxaliplatin plus irinotecan and leucovorin-modulated 5-fluorouracil triplet regimen every other week: a dose-finding study in patients with advanced gastrointestinal malignancies.

Comella P, Casaretti R, De Rosa V, Avallone A, Izzo F, Fiore F, Lapenta L, Comella G.

Ann Oncol. 2002 Dec;13(12):1874-81.

PMID: 12453855 [PubMed - indexed for MEDLINE]

11:

Controlled ribozyme targeting demonstrates an antiapoptotic effect of carcinoembryonic antigen in HT29 colon cancer cells.

Soeth E, Wirth T, List HJ, Kumbhani S, Petersen A, Neumaier M, Czubayko F, Juhl H.

Clin Cancer Res. 2001 Jul;7(7):2022-30.

PMID: 11448920 [PubMed - indexed for MEDLINE]

12:

Effect of 5-fluorouracil on carcinoembryonic antigen expression and shedding at clonal level in colon cancer cells.

Aquino A, Prete SP, Guadagni F, Greiner JW, Giuliani A, Orlando L, Masci G, De Santis S, Bonmassar E, Graziani G.

Anticancer Res. 2000 Sep- Oct;20(5B):3475-84.

PMID: 11131650 [PubMed - indexed for MEDLINE]

13:

Oxaliplatin. A review of its pharmacological properties and clinical efficacy in metastatic colorectal cancer and its potential in other malignancies.

Culy CR, Clemett D, Wiseman LR.

Drugs. 2000 Oct;60(4):895-924. Review.

PMID: 11085200 [PubMed - indexed for MEDLINE]

14:

Weekly oxaliplatin, high-dose folinic acid and 24h-5-fluorouracil (FUFOX) as salvage therapy in metastatic colorectal cancer patients pretreated with irinotecan and folinic acid/5-fluorouracil regimens.

Moehler M, Hoffmann T, Hildner K, Siebler J, Galle PR, Heike M.

Z Gastroenterol. 2002 Dec;40(12):957-64.

PMID: 12564419 [PubMed - indexed for MEDLINE]

15:

Hepatic arterial infusion with oxaliplatin, folinic acid, and 5-fluorouracil in patients with hepatic metastases from colorectal cancer: role of carcino-embryonic antigen in assessment of response.

Kern W, Beckert B, Lang N, Waggershauser T, Braess J, Schalhorn A, Hiddemann W.

Anticancer Res. 2000 Nov-Dec;20(6D):4973-5.

PMID: 11326650 [PubMed - indexed for MEDLINE]

16:

Down-regulation of thymidylate synthase expression and its steady-state mRNA by oxaliplatin in colon cancer cells.

Yeh KH, Cheng AL, Wan JP, Lin CS, Liu CC.

Anticancer Drugs. 2004 Apr;15(4):371-6.

PMID: 15057142 [PubMed - indexed for MEDLINE]

17:

The clinical and cost-effectiveness of oxaliplatin and capecitabine for the adjuvant treatment of colon cancer: systematic review and economic evaluation.

Pandor A, Eggington S, Paisley S, Tappenden P, Sutcliffe P.

Health Technol Assess. 2006 Nov;10(41):iii-iv, xi-xiv, 1-185. Review.

PMID: 17049138 [PubMed - indexed for MEDLINE]

18:

Combined effects of protein kinase inhibitors and 5-fluorouracil on CEA expression in human colon cancer cells.

Prete SP, Rossi L, Correale PP, Turriziani M, Baier S, Tamburrelli G, De Vecchis L, Bonmassar E, Aquino A.

Pharmacol Res. 2005 Aug;52(2):167-73.

PMID: 15967383 [PubMed - indexed for MEDLINE]

19:

Impact of the oxaliplatin-5 fluorouracil-folinic acid combination on respective intracellular determinants of drug activity.

Fischel JL, Formento P, Ciccolini J, Rostagno P, Etienne MC, Catalin J, Milano G.

Br J Cancer. 2002 Apr 8;86(7):1162-8.

PMID: 11953866 [PubMed - indexed for MEDLINE]

20:

Oxaliplatin combined to 5-fluorouracil and folinic acid: an effective therapy in patients with advanced colorectal cancer.

Gerard B, Bleiberg H, Van Daele D, Gil T, Hendlisz A, Di Leo A, Fernez B, Brienza S.

Anticancer Drugs. 1998 Apr;9(4):301-5.

PMID: 9635919 [PubMed - indexed for MEDLINE]

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